On March 31, 2021 the COVID-19 International Research Team hosted their virtual annual symposium. Keynote speakers included Dr. Duncan MacCannell from the CDC, Dr. Sharon Peacock from the University of Cambridge, David Jaffray and Andrew Futreal from MD Anderson Cancer Center, and Don Milton from the University of Maryland School of Public Health. Dr. Kyle Hernandez from the Center for Translational Data Science moderated a session with speakers from NASA Ames Research Center, Signature Science, Real Networks, and Baylor College of Medicine on modeling, masks, and microbiomes.